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Join an NIEHS Study
National Institute of Environmental Health Sciences

Studies

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Studies Open for Recruitment

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Adult and Juvenile Myositis

This study will evaluate subjects with adult- and childhood-onset myositis to learn more about their causes, and the immune system changes and medical problems associated with them. Myositis is an inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability.
This study will evaluate subjects with adult- and childhood-onset myositis to learn more about their causes, and the immune system changes and medical problems associated with them. Myositis is an inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability.
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Calcinosis Study

This study is a clinical trial of intravenous sodium thiosulfate, a drug being tested for efficacy and safety in patients who have moderate to extensive calcinosis associated with juvenile and adult dermatomyositis.
This study is a clinical trial of intravenous sodium thiosulfate, a drug being tested for efficacy and safety in patients who have moderate to extensive calcinosis associated with juvenile and adult dermatomyositis.
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COVID-19 Antibody Detection Study

This yearlong study will test adult volunteers for antibodies in their blood that indicate exposure to SARS-CoV-2, the virus that causes COVID-19.
This yearlong study will test adult volunteers for antibodies in their blood that indicate exposure to SARS-CoV-2, the virus that causes COVID-19.
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Demystifying a Girl's First Period

Why is it so unpredictable?

Moms, help your daughters prepare for puberty by enrolling them in a new study called a Girl’s First Period.
Moms, help your daughters prepare for puberty by enrolling them in a new study called a Girl’s First Period.
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E-Cigs and Smoking

Researchers are trying to develop new biomarkers of tobacco smoke exposure and e-cigarette use.
Researchers are trying to develop new biomarkers of tobacco smoke exposure and e-cigarette use.
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Immunity Cells in Blood

What Is the Response of Immune Cells From the Bloodstream?

The Immunity Cells in Blood Study aims to determine the response of immune cells from the bloodstream.
The Immunity Cells in Blood Study aims to determine the response of immune cells from the bloodstream.
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Inherited Reproductive Disorders Study

The goal of this study is to learn more about the body’s regulation of puberty and reproduction. Scientists will study people who have an abnormality in certain hormone levels, which may result in specific differences in fetal development, irregular timing of puberty, or abnormal fertility.
The goal of this study is to learn more about the body’s regulation of puberty and reproduction. Scientists will study people who have an abnormality in certain hormone levels, which may result in specific differences in fetal development, irregular timing of puberty, or abnormal fertility.
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MYORISK Study

Do you have polymyositis or dermatomyositis?

This study intends to investigate the genetic and environmental risk factors involved in the development of myositis, an autoimmune muscle disease that causes chronic muscle weakness.
This study intends to investigate the genetic and environmental risk factors involved in the development of myositis, an autoimmune muscle disease that causes chronic muscle weakness.
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NHALES: Asthma Study

Get Your Asthma Under Control

NHALES stands for Natural History of Asthma with Longitudinal Environmental Sampling. Your participation in the NHALES Study will contribute to research on how the environment affects the human body and asthma. Please consider joining today.
NHALES stands for Natural History of Asthma with Longitudinal Environmental Sampling. Your participation in the NHALES Study will contribute to research on how the environment affects the human body and asthma. Please consider joining today.
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Personalized Environment and Genes Study (PEGS)

Powerful science for integrating genomic and environmental data to understand human health

The goal of this study is to learn more about how our environment, diet, lifestyle and genes affect our health.
The goal of this study is to learn more about how our environment, diet, lifestyle and genes affect our health.
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RSV Infection and Asthma

NIEHS scientists will explore whether there is a difference in lung cells from healthy and asthmatic participants and how these cells respond to exposure to respiratory syncytial virus (RSV), a very common virus that leads to cold-like symptoms. The study will also evaluate if a protein in lung cells called TGF-Beta increases risk of infection with RSV.
NIEHS scientists will explore whether there is a difference in lung cells from healthy and asthmatic participants and how these cells respond to exposure to respiratory syncytial virus (RSV), a very common virus that leads to cold-like symptoms. The study will also evaluate if a protein in lung cells called TGF-Beta increases risk of infection with RSV.
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Smoke Exposure COVID-19 Study

This study will help determine if smoking increases the risk of developing coronavirus disease 2019 (COVID-19), and will evaluate the effect of COVID-19 on the immune system of people who smoke.
This study will help determine if smoking increases the risk of developing coronavirus disease 2019 (COVID-19), and will evaluate the effect of COVID-19 on the immune system of people who smoke.
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The Women's Reproductive Health Study

Part of the Demystifying a Girl’s First Period Study

Help us understand how to detect signs of hormone problems and prevent reproductive health disorders in women.
Help us understand how to detect signs of hormone problems and prevent reproductive health disorders in women.
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Women's Health Awareness Vaccine Confidence Study

If you are a Black/African American woman or man over the age of 18 and living in North Carolina, we want to hear from you.
If you are a Black/African American woman or man over the age of 18 and living in North Carolina, we want to hear from you.

Open Studies By Invitation Only

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Inflammatory Response to DNA Damage

The gene p53 suppresses cancer and inflammation in the body, and NIEHS researchers speculate that changes in p53 lead to changes in inflammation and the ability to repair DNA damage. This study wants blood samples from participants to find out how the changes in p53 lead to these conditions.
  • Status: Open
  • Sex: Both
  • Age: 18 - 45
  • Compensation:
  • Location: Durham, NC
The gene p53 suppresses cancer and inflammation in the body, and NIEHS researchers speculate that changes in p53 lead to changes in inflammation and the ability to repair DNA damage. This study wants blood samples from participants to find out how the changes in p53 lead to these conditions.
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Inflammatory Response to Endotoxin

Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation. Researchers are interested in studying how the body responds to certain environmental factors, and whether the body’s response can contribute to chronic illnesses or diseases such as asthma and certain types of cancer.
  • Status: Open
  • Sex: Both
  • Age: 18+
  • Compensation:
  • Location: Durham, NC
Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation. Researchers are interested in studying how the body responds to certain environmental factors, and whether the body’s response can contribute to chronic illnesses or diseases such as asthma and certain types of cancer.
Studies Not Currently Recruiting

Can’t Find the Right Study For You?

If you didn’t find an NIEHS study to join, there are other studies you can consider. Visit  ClinicalTrials.gov  and  ResearchMatch.org.