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The purpose of this research study is to build a collection of human biological samples and health data. Researchers will use these samples to develop, test, and practice various laboratory procedures. Testing may include improving the processing of blood or urine samples, how long samples can be kept in a deep freeze, and how samples react under different conditions over time.
Sex: Both
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
This is a study on the controlled exposure of BPA and its effects on the body.
Sex: Both
Age: 25 - 45
Location: Durham, NC
Age: 25 - 45
Location: Durham, NC
Researchers are investigating whether black cohosh may affect folate and B12 levels, anemia, and metabolomics profiles. They are also investigating whether black cohosh induces genetic changes.
Sex: Female
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
Researchers want to study healthy adults who have genes that may affect their endothelial function. More information on these genes may provide more information on genetic risk for certain diseases.
Sex: Both
Age: 18 - 65
Location: Durham, NC
Age: 18 - 65
Location: Durham, NC
Girls seem to be going through puberty a lot earlier these days. Doctors think it may be related to body weight. Are you concerned that your daughter is overweight and may start puberty too soon?
Sex: Female
Age: 8-14
Location: Durham, NC
Age: 8-14
Location: Durham, NC
A pilot study designed to measure BPA levels before and after occupational exposure to thermal paper used in cash registers.
Sex: Both
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
This study is a clinical trial of intravenous sodium thiosulfate, a drug being tested for efficacy and safety in patients who have moderate to extensive calcinosis associated with juvenile and adult dermatomyositis.
Sex: Both
Age: 7+
Location: Multiple Locations
Age: 7+
Location: Multiple Locations
Many women develop irregular menstrual cycles which may make it difficult to become pregnant and increase the risk of osteoporosis. Why do exercise and diet have this effect in some women but not others? This study will help us understand how nutrition, exercise, and the environment affect women's reproductive cycles.
Sex: Female
Age: 18 - 28
Location: Durham, NC
Age: 18 - 28
Location: Durham, NC
How Does Daily Exposure to Everyday Household and Personal Products Effect You?
Sex: Female
Age: 35-74
Location: Durham, NC
Age: 35-74
Location: Durham, NC
Evidence suggests that exposure to cockroach allergen might be the most important risk factor for asthma in inner-city households.
Sex: Both
Age: 21+
Location: Durham, NC
Age: 21+
Location: Durham, NC
This yearlong study will test adult volunteers for antibodies in their blood that indicate exposure to SARS-CoV-2, the virus that causes COVID-19.
Sex: Both
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
The COX-2 gene may help decide the balance of cell types that the body makes as part of the immune system. It may also play a role in certain immune system diseases. Researchers want to see how COX-2 affects the cells in the immune system.
Sex: Both
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
This study will determine whether use of an in-home test kit results in decreased dust mite allergen levels in homes of children who are sensitive or allergic to dust mites.
Sex: Both
Age: 5 - 15
Location: Durham, NC
Age: 5 - 15
Location: Durham, NC
If you are a man or woman, 18-55 years old, living in the Raleigh-Durham-Chapel Hill area, and smoke cigarettes or use an electronic nicotine delivery system (e-cigarette), please join an important study on smokers.
Sex: Both
Age: 18-55
Location: Durham, NC
Age: 18-55
Location: Durham, NC
To identify and understand how environmental exposures can alter uterine function in women and may result in infertility and disease.
Sex: Female
Age: 18 - 35
Location: Durham, NC
Age: 18 - 35
Location: Durham, NC
The purpose of this study is to learn how an adult’s environment may cause problems with their hormones and reproductive system.
Sex: Both
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
This study evaluated allergen levels and their predictors in day-care facilities in two North Carolina counties. The purpose was to determine whether further study of day-care facilities on a regional or national basis is warranted and to identify associations that might be important to evaluate in larger studies.
Sex: Female
Age:
Location: Durham, NC
Age:
Location: Durham, NC
The purpose of the study is to learn how to make homes more supportive of healthy eating and physical activity.
Sex: Female
Age: 35 - 65
Location: Other
Age: 35 - 65
Location: Other
The Immunity Cells in Blood Study aims to determine the response of immune cells from the bloodstream.
Sex: Both
Age:
Location: Durham, NC
Age:
Location: Durham, NC
Innate immunity is the process by which white blood cells and other parts of the immune system sense and respond to potential infections by causing an inflammation. Researchers are interested in studying how the body responds to certain environmental factors, and whether the body’s response can contribute to chronic illnesses or diseases such as asthma and certain types of cancer.
Sex: Both
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
ICAS Study evaluates the effectiveness of two types of interventions to reduce the prevalence and severity of asthma in children.
Sex: Female
Age: 5 - 11
Location: Durham, NC
Age: 5 - 11
Location: Durham, NC
Vitamin D supplementation may be a low-cost intervention that improves menstrual cycle function and fertility.
Sex: Female
Age: 19-40
Location: Durham, NC
Age: 19-40
Location: Durham, NC
NIEHS researchers theorize that changes in the surface proteins of cells called receptors may predispose people to diseases, such as heart disease, arthritis, and diabetes. The volunteers of this study underwent tests to determine how these changes or variants lead to illness.
Sex: Both
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
This study attempts to determine if environmental and geographic exposures may be related to the development of myositis during military service.
Sex: Both
Age: 18+
Location: Bethesda, MD
Age: 18+
Location: Bethesda, MD
NHANES allowed researchers to examine the role of diet, obesity, diabetes, and genetics in the development of allergic disease.
Sex: Both
Age: 1-74
Location: Durham, NC
Age: 1-74
Location: Durham, NC
NSLAH measures levels of lead in dust, soil, and paint, and the levels of various indoor allergens in floor and bedding dust.
Sex: Both
Age: 18-65
Location: Durham, NC
Age: 18-65
Location: Durham, NC
NHALES stands for Natural History of Asthma with Longitudinal Environmental Sampling. Your participation in the NHALES Study will contribute to research on how the environment affects the human body and asthma. Please consider joining today.
Sex: Both
Age: 18 - 60
Location: Durham, NC
Age: 18 - 60
Location: Durham, NC
This project will look at how oxidative stress occurs in smokers compared to non-smokers.
Sex: Both
Age: 18-50
Location: Durham, NC
Age: 18-50
Location: Durham, NC
The goal of this study is to find out whether polycystic ovary syndrome in twins is caused by genetics, environmental triggers or a combination of both.
Sex: Female
Age: 18+
Location: Other
Age: 18+
Location: Other
Researchers are studying the differences in immune response between a person with psoriasis, a person with chronic inflammatory disease and a healthy person.
Sex: Both
Age: 18 - 70
Location: Durham, NC
Age: 18 - 70
Location: Durham, NC
The research team will study the genetic and environmental risk factors in the development of autoimmune diseases in twins and same-sex siblings, in which one has the disease and the other does not.
Sex: Both
Age: All
Location: Bethesda, MD
Age: All
Location: Bethesda, MD
NIEHS scientists will explore whether there is a difference in lung cells from healthy and asthmatic participants and how these cells respond to exposure to respiratory syncytial virus (RSV), a very common virus that leads to cold-like symptoms. The study will also evaluate if a protein in lung cells called TGF-Beta increases risk of infection with RSV.
Sex: Both
Age: 18-60
Location: Durham, NC
Age: 18-60
Location: Durham, NC
Researchers are interested in developing a registry protocol to obtain biologic and environmental samples anonymously from adult volunteers for use in laboratory tests and studies. The samples will be used to determine if new tests are sufficiently valid and precise to be used in research studies and for quality control purposes.
Sex: Both
Age: 18+
Location: Durham, NC
Age: 18+
Location: Durham, NC
This study will help determine if smoking increases the risk of developing coronavirus disease 2019 (COVID-19), and will evaluate the effect of COVID-19 on the immune system of people who smoke.
Sex: Both
Age: 30 - 55
Location: Durham, NC
Age: 30 - 55
Location: Durham, NC
Anti-müllerian hormone (AMH) is a hormone produced in the ovaries. Researchers are investigating the possibility of developing lab assays to measure AMH in urine.
Sex: Female
Age: 25-29
Location: Durham, NC
Age: 25-29
Location: Durham, NC
Last Reviewed: March 26, 2025