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MYORISK Study

Environmental Risk Factors for the Anti-synthetase Syndrome

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Do you have polymyositis or dermatomyositis?

A study is being conducted for individuals with the autoimmune disease polymyositis or dermatomyositis. The goal of this research study is to better understand the environmental risk factors that may result in these diseases. Compensation is provided for participants.

Who Can Participate?

  • Adults or children who have been diagnosed with polymyositis or dermatomyositis within the last two years.
  • Healthy friends or cousins of individuals with polymyositis or dermatomyositis.

What Is Required?

  • Completing surveys, collecting a house dust sample, a single clinic visit, and a blood draw.
  • You may enroll at the Clinical Center at the National Institutes of Health (NIH) in Bethesda, Maryland, or an associated collaborating center in Maryland or Pennsylvania; the NIEHS Clinical Research Unit in Research Triangle Park, North Carolina; or your local doctor’s office.
  • There is no charge for evaluations and medical tests at NIH.

Who Is Running the Study?

The study is run by physicians at the National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health, U.S. Department of Health and Human Services.

Lead Researcher

Frederick W. Miller, M.D., Ph.D.

Frederick W. Miller, M.D., Ph.D.

Tel 984-287-3593
millerf@mail.nih.gov
Learn More About Frederick W. Miller, M.D., Ph.D.

Frederick W. Miller, M.D., Ph.D. oversees researchers in his group as well as others in national and international consortia that evaluate and conduct a wide range of basic and clinical studies on adult and juvenile autoimmune diseases. His interests are broad and he wishes to understand what triggers these diseases and how to best assess, treat, cure and ultimately prevent them. He obtained his M.D. and Ph.D. from Case Western Reserve University, went on to medical residencies at Emory and Stanford, and then did rheumatology and immunology training at the NIH. His work in the field of autoimmune diseases spans over three decades and involves many aspects of the phenotypes, environmental risk factors, epidemiology, immunology, genetics, pathogenesis, evaluation and treatment of immune-mediated diseases. He has focused much of his work on autoimmune muscle diseases.

Research Page

Adult Volunteers

Adam I. Schiffenbauer, M.D.

Adam Schiffenbauer, M.D. is an Associate Research Physician in the Environmental Autoimmunity Group, and an adult rheumatologist with an expertise in myositis. He received his B.A. from The University of Chicago and his M.D. from Pennsylvania State University. He completed an internal medicine residency at George Washington University, and his fellowship in rheumatology at the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD. He then joined Dr. Frederick Miller’s group in NIEHS in Bethesda, MD. Dr. Schiffenbauer’s work has been focused on environmental and genetic risk factors, phenotypes, pathogenesis, advanced imaging, evaluation, and therapeutic trials in myositis.

Pediatric Volunteers

Lisa Rider, M.D.

Lisa Rider, M.D. is Deputy Chief of the Environmental Autoimmunity Group, and a pediatric rheumatologist with an international reputation for her work on juvenile myositis. She received her B.A. and M.D. from Duke University, completed a pediatrics residency at Seattle Children’s Hospital of University of Washington, and her fellowship in pediatric rheumatology at Seattle Children’s Hospital, Children’s National Medical Center, Washington D.C. and the National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD.  She then joined Dr. Frederick Miller’s group in the Center for Biologics Evaluation and Research, Food and Drug Administration and subsequently moved to NIEHS in Bethesda, MD.  Dr. Rider’s work has been focused on environmental and genetic risk factors, phenotypes, pathogenesis, outcomes, evaluation, and therapeutic trials in juvenile myositis and other systemic pediatric rheumatic diseases. She has co-led national and international myositis collaborative research groups, and authored from than 170 research publications, reviews, books, and book chapters. She has received several awards of distinction.

Research Page

For More Information About This Study

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