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Smoke Exposure COVID-19 Study

A Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19

Studies Seeking Participants Icon Studies Seeking Participants Location icon Residents of North Carolina 30 - 55 Ages 30 - 55 Gender Icon All Genders
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This study will help determine if smoking increases the risk of developing coronavirus disease 2019 (COVID-19), and will evaluate the effect of COVID-19 on the immune system of people who smoke.

Who Can Participate?

  • Men and women ages 30-55
  • Current cigarette or vaping device users
  • No prior or current cancer diagnosis
  • A body mass index of less than 35

What Is Required?

  • Six visits to donate blood, saliva, nasal cell and cheek cell samples, and answer medical questionnaires
  • Antibody testing to see if you had COVID-19 in the past
  • Ability to travel to the National Institute of Environmental Health Sciences (NIEHS) Clinical Research Unit in Research Triangle Park, North Carolina
  • Participants compensated up to $700

Who Is Running the Study?

A team, led by Doug Bell, Ph.D., and Stavros Garantziotis, M.D., at the National Institute of Environmental Health Sciences (NIEHS) Clinical Research Unit in Research Triangle Park, North Carolina.

Lead Researchers

Douglas A. Bell, Ph.D.

Douglas A. Bell, Ph.D.

Tel 984-287-3862
Learn More About Douglas A. Bell, Ph.D.

Douglas A. Bell, Ph.D. leads the Environmental Epigenomics Group in the Immunity Inflammation and Disease Laboratory, NIEHS. He works on functional analysis of human genetic variation, epigenetic features and environmental response gene expression in relation to human susceptibility. His group uses CyTOF, single cell RNA-seq, and whole genome methylation analysis to examine the relationship between environmental exposure—including viral exposure, altered DNA methylation and functional changes in human immune cells in the blood. He has a B.S. degree from Cornell University and a Ph.D. in Environmental Biology from the University of North Carolina at Chapel Hill in 1988. Following postdoctoral fellowships at UNC-CH and U.S. Environmental Protection Agency he joined the National Institute of Environmental Health Sciences in 1990 becoming a Senior Investigator in 1996.

Research Webpage

Stavros Garantziotis, M.D.

Stavros Garantziotis, M.D. is passionate about finding cures for chronic lung disease like asthma, COPD and pulmonary fibrosis. He believes that if we can understand the mechanism of disease development for every individual patient, we can design intelligent and effective treatment with less side effects. Dr. Garantziotis obtained his medical degree at the Albert-Ludwigs-University in Germany. He trained in Internal Medicine at the Albert Einstein College of Medicine in New York and in Pulmonary and Critical Care Medicine at Duke University Medical Center, where he was a faculty member before joining the NIEHS to direct the Clinical Research Unit.

Research Webpage

For More Information About This Study

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