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Inflammatory Response to DNA Damage

Study of the Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

Studies Seeking Participants Icon Studies Seeking Participants Location icon Residents of North Carolina 18 - 45 Ages 18 - 45 Gender Icon All Genders
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    4. Study Overview

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Studies Seeking Participants IconStudies Seeking Participants Location iconResidents of North Carolina 18 - 45Ages 18 - 45 Gender IconAll Genders

The gene p53 suppresses cancer and inflammation in the body, and NIEHS researchers speculate that changes in p53 lead to changes in inflammation and the ability to repair DNA damage. This study wants blood samples from participants to find out how the changes in p53 lead to these conditions.

Who Can Participate?

Enrolling by invitation only.

Healthy volunteers as defined by the International Red Cross guidelines (Healthy means that an individual feels well and can perform normal activities. If the individual has a chronic condition such as diabetes or high blood pressure, healthy also means that they are being treated and the condition is under control).

What Is Required?

  • The study will involve one visit of 45 to 60 minutes. 
  • Participants will be screened with a brief physical examination, questionnaire about any medications or other drugs (e.g., cigarettes) they may be taking.
  • Participants will provide a blood sample for research purposes.

Who Is Running the Study?

The study is run by physicians at the  National Institute of Environmental Health Sciences (NIEHS), National Institutes of Health, U.S. Department of Health and Human Services.

Lead Researcher

Daniel Menendez Rendon, Ph.D.

Daniel Menendez Rendon, Ph.D.

Tel 984-287-4105
menendez@niehs.nih.gov

For More Information About This Study